Gonadal Dysgenesis	Karyotype	Gonad	Genitalia	Clinical/Notes/Treatment
Turner's Syndrome	45XO or variant	streaks	female	sexual infantalism, short stature, primary amenorrhoea, various inconstant physical features
Klinefelter's Syndrome	XXY	seminiferous tubule dysgenesis	male	small firm testes, apermic, tall (long legs), gynaecomastia in 50%, may have mental and emotional difficulties
True hermaphroditism	46XX, 46XY or mosaic	ovary, testis or ovotestis	ambig. or male	variable internal and external organs, phallus, bifid scrotum, hypospadias. Surgery according to sex of rearing.
Mixed gonadal dysgenesis	mosaic (XO/XY)	streak + UDT	ambig. or female	short stature, mixed internal organs. Rear as female. Gonadectomy for cancer risk and virilisation.
Pure gonadal dysgenesis	46XY   46XX	streak   streak	female female	variable clitoral hypertrophy, failure of sexual development, primary amenorrhoea, gonadal cancer risk. no clitoral hypertrophy, no gonadal cancer risk.
46XX Male	46XX	testes	male or ambig.	infertility, hypospadias, UDT, short stature. Genital surgery needed. Rare.